4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER

4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER - Names and Identifiers

Name	4-Bromomethyl-benzoic acid tert-butyl ester
Synonyms	t-butyl-4-bromomethylbenzoate tert-butyl 4-(bromomethyl)benzoate tert-Butyl 4-(bromomethyl)benzoate TERT-BUTYL P-(BROMOMETHYL) BENZOATE 4-Benzoic acid mono tert-butyl ester 1,1-DIMETHYLETHYL 4-(BROMOMETHYL)BENZOATE 4-Bromomethyl-benzoic acid tert-butyl ester 4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER 4-(BROMOMETHYL)-BENZOIC ACID, 1,1-DIMETHYLETHYL ESTER 4-(Bromomethyl)-Benzoic Acid, 1,1-Dimethylethyl Ester benzoic acid 4-(bromomethyl)-,1,1-dimenthylethyl ester
CAS	108052-76-2
EINECS	691-573-1
InChI	InChI=1/C12H15BrO2/c1-12(2,3)15-11(14)10-6-4-9(8-13)5-7-10/h4-7H,8H2,1-3H3

4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER - Physico-chemical Properties

Molecular Formula	C12H15BrO2
Molar Mass	271.15
Density	1.313±0.06 g/cm3(Predicted)
Melting Point	53-55 °C
Boling Point	320.9±25.0 °C(Predicted)
Flash Point	147.9°C
Vapor Presure	0.000308mmHg at 25°C
Appearance	White solid
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.537
MDL	MFCD04973450

4-BROMO METHYL BENZOIC ACID MONO TERT-BUTYL ESTER - Reference Information

use

tert-butyl 4-bromomethyl benzoate is an intermediate for the synthesis of acaricide acaricide acardol.

production method

the preparation method is to add 0.56g tert-butanol, 0.395g pyridine and 1.75g 4-bromomethylbenzoyl chloride to a three-mouth bottle equipped with a stirrer and thermometer, and react at 10~30 ℃ for 5h. After the reaction, add 10mL of water to the reaction bottle, move to the separatory funnel, and extract with ethyl acetate. The extracts were combined, washed with dilute acid, separated into acid water layer and then desoluted under reduced pressure to obtain 0.98g of tert-butyl 4-bromomethylbenzoic acid with 72.0% yield.

Last Update：2024-04-09 20:52:54